Evidence-certainty justification record ======================================= StatMedAnalysis | Original downloadable worksheet | 6 November 2026 Explain outcome-specific certainty judgments with traceable reasons. How to use this worksheet Define one outcome and comparison before assessing certainty. Review risk of bias, inconsistency, indirectness, imprecision and publication bias using the appropriate GRADE approach. Record the evidence and magnitude of each judgment. Avoid counting the same underlying concern twice without explanation. Save a working copy and keep the original blank version. Use public, hypothetical or aggregate information only; do not enter patient identifiers, credentials or confidential records. Keep source evidence in your approved project workspace. Mark unresolved text fields UNKNOWN or NOT REPORTED with a reason; never substitute zero for an unknown count. Project/version __________________ Prepared by role/date __________________ Working fields 1. Outcome, comparison and time horizon Response/evidence: _________________________________________________________ ___________________________________________________________________________ 2. Study designs and body of evidence Response/evidence: _________________________________________________________ ___________________________________________________________________________ 3. Risk-of-bias rationale Response/evidence: _________________________________________________________ ___________________________________________________________________________ 4. Inconsistency and indirectness rationale Response/evidence: _________________________________________________________ ___________________________________________________________________________ 5. Imprecision relative to decision thresholds Response/evidence: _________________________________________________________ ___________________________________________________________________________ 6. Publication-bias evidence Response/evidence: _________________________________________________________ ___________________________________________________________________________ 7. Other applicable GRADE considerations Response/evidence: _________________________________________________________ ___________________________________________________________________________ 8. Overall judgment and explanation Response/evidence: _________________________________________________________ ___________________________________________________________________________ Hypothetical worked case A fictional review has a wide interval spanning meaningful benefit and harm. The team records the decision thresholds and information size when considering imprecision instead of downgrading merely because p exceeds 0.05. Decision rule and limitations Finalize certainty separately for each important outcome and explain each change from the starting level. A completed table is not a substitute for the underlying judgments. Decision _______________________ Remaining uncertainty ____________________ Next action ____________________ Owner / review date ______________________ Independent check and discrepancy resolution _______________________________ Official method or reporting reference checked 6 November 2026 https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-14 This is an original planning aid, not an official checklist, validated instrument, clinical recommendation or certificate of expert approval. Apply the referenced guidance to the specific design and record any additional requirements.