Target-population transport worksheet ===================================== StatMedAnalysis | Original downloadable worksheet | 6 November 2026 Assess whether a study result can inform a different population. How to use this worksheet Describe the source and intended target populations using eligibility, setting and calendar time. Identify plausible effect modifiers and compare their distributions or support. Distinguish a descriptive similarity argument from a formal transport analysis. Record what target information is missing. Save a working copy and keep the original blank version. Use public, hypothetical or aggregate information only; do not enter patient identifiers, credentials or confidential records. Keep source evidence in your approved project workspace. Mark unresolved text fields UNKNOWN or NOT REPORTED with a reason; never substitute zero for an unknown count. Project/version __________________ Prepared by role/date __________________ Working fields 1. Source population and recruitment Response/evidence: _________________________________________________________ ___________________________________________________________________________ 2. Target population and decision Response/evidence: _________________________________________________________ ___________________________________________________________________________ 3. Candidate effect modifiers Response/evidence: _________________________________________________________ ___________________________________________________________________________ 4. Measured distribution differences Response/evidence: _________________________________________________________ ___________________________________________________________________________ 5. Target covariate data availability Response/evidence: _________________________________________________________ ___________________________________________________________________________ 6. Support and measurement comparability Response/evidence: _________________________________________________________ ___________________________________________________________________________ 7. Transport method and assumptions Response/evidence: _________________________________________________________ ___________________________________________________________________________ 8. Limits on the proposed claim Response/evidence: _________________________________________________________ ___________________________________________________________________________ Hypothetical worked case A fictional study recruits younger adults from specialist centers, while the intended target includes older community patients. Similar average age after weighting would not address an unmeasured severity difference or absent support at extreme ages. Decision rule and limitations Restrict claims when key modifiers or target support are unknown. A generalizability statement must name the population and assumptions rather than declare results universally applicable. Decision _______________________ Remaining uncertainty ____________________ Next action ____________________ Owner / review date ______________________ Independent check and discrepancy resolution _______________________________ Official method or reporting reference checked 6 November 2026 https://miguelhernan.org/whatifbook This is an original planning aid, not an official checklist, validated instrument, clinical recommendation or certificate of expert approval. Apply the referenced guidance to the specific design and record any additional requirements.