Research Workbench

Diagnostic Accuracy Calculator

Check sensitivity, specificity, and predictive-value denominators using aggregate test counts.

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Calculate descriptive diagnostic proportions from a single threshold and reference standard. Use one independent observation per participant. Defaults are fictional; this is not a tool for diagnosing an individual.

Calculation results

Sensitivity
80%
Specificity
85%
Positive predictive value
72.7273%
Negative predictive value
89.4737%
Reference-positive proportion in this sample
33.3333%

Confidence intervals are not calculated. Predictive values depend on the sampled population and cannot automatically be transferred to another setting.

Denominators matter

Sensitivity = TP/(TP+FN); specificity = TN/(TN+FP); PPV = TP/(TP+FP); NPV = TN/(TN+FN). A zero denominator is displayed as not estimable. Unverified, indeterminate, or missing reference results require explicit handling and cannot simply be treated as negatives. Case-control diagnostic sampling usually prevents direct interpretation of predictive values as those in clinical practice.

FDA: reporting diagnostic test studies · Read the practical guide · Download blank worksheet (TXT)