Practical guides · Page 18

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Check Expected Counts Before a Contingency-Table Test

Audit category counts, independence, and sparse cells before interpreting a categorical association test.

Audit a Research Data Dictionary Before Analysis

Match each dataset column to a clear definition, value labels, missing-value rules, and a traceable derivation.

Audit Two-Rater Agreement Before Reporting Kappa

Build a labeled agreement table and interpret Cohen’s kappa alongside observed agreement and category frequencies.

Summarize an Ordinal Scale Without Hiding Its Categories

Preserve ordered response labels, denominators, and scoring rules when describing ordinal research outcomes.

Use Discordant Pairs in an Exact McNemar Test

Preserve matched binary outcomes and separate directional change from overall agreement before testing.

Document a Reproducible Randomization Sequence Safely

Record generation settings and independent checks while preserving allocation concealment during enrollment.

Use File Checksums to Verify a Research Handoff

Record SHA-256 digests to detect byte-level file changes while keeping content validation and access control separate.

Use Weight-Based Effective Sample Size as a Diagnostic

Inspect unequal weights without confusing a simple effective sample calculation with full survey-design precision.

Check Variable Names Without Silently Changing Their Meaning

Find duplicate, ambiguous, and incompatible column names before renaming research data fields.

Assess Measurement Agreement Beyond Correlation

Plan paired differences, limits of agreement, and acceptable error before comparing two measurement methods.

Define Analysis Populations Before Building Tables

Write explicit membership and grouping rules so participant counts remain traceable across efficacy, safety, and sensitivity analyses.

How to Choose a Biostatistics Consultant for Medical Research

Compare statistical support by study fit, written scope, reproducible deliverables, data handling, and revision terms—with a downloadable checklist.