Research workflows

Follow a worked research decision using linked guides, free calculators, downloadable worksheets and primary references.

Validate a clinical prediction model

Check whether model predictions hold up in the intended patient population. Start with the validation sample, then examine ranking, probability accuracy and performance at a decision threshold.

Audit a systematic review search

Trace a search from the strategy and database exports to the records selected for screening. Use known eligible records to investigate omissions and document the decisions behind the final count.

Compare event rates across groups

Build comparable event counts and time at risk, estimate a crude rate ratio, and check whether differences in population composition call for a standardized comparison.