Fisher independent p-value combination
Combine independent p-values for an omnibus global-null assessment.
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Enter 2–100 p-values strictly greater than zero and at most one. Reported zero p-values must be replaced with valid higher-precision values, not arbitrary tiny numbers.
The starting values are hypothetical. Results update as you edit. Use aggregate or synthetic inputs only.
Calculation results
- Fisher statistic
- 18.866968
- Degrees of freedom
- 6
- Combined p under independence
- 0.0043943035
How to interpret the output
Fisher statistic −2×sum(log p) has chi-square distribution with 2k degrees of freedom under independent continuous uniform-null p-values. Dependence and selective inclusion invalidate that reference. Combining p-values does not estimate an effect or establish consistent effect direction.
Method referenceSource checked 2026-11-06. Read the reproducible calculator validation report.